RAB12 antibody
Quick Overview for RAB12 antibody (ABIN7118189)
Target
Reactivity
Host
Clonality
Conjugate
Application
-
-
Purpose
- RAB12 antibody
-
Purification
- Immunogen affinity purified
-
Purity
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- RAB12, member RAS oncogene family
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB: 1:500-1:2000, IP: 1:500-1:1000 , IHC: 1:20-1:200, IF: 1:50-1:500
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freeze / thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- -20°C for 12 months
-
Expiry Date
- 12 months
-
-
- RAB12 (RAB12, Member RAS Oncogene Family (RAB12))
-
Alternative Name
- RAB12
-
Background
-
Synonyms: Ras-related protein Rab-12|RAB12
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy(By similarity).
-
Molecular Weight
- 28 kDa
-
Gene ID
- 201475
-
UniProt
- Q6IQ22
Target
-