RAB35 antibody

Catalog No. ABIN7118213

The Rabbit Polyclonal anti-RAB35 antibody has been validated for ELISA, WB, IHC, IF and IP. It is suitable to detect RAB35 in samples from Human, Rat and Mouse.

Quick Overview for RAB35 antibody (ABIN7118213)

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB35 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-RAB35 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RAB35, member RAS oncogene family

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for RAB35

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Alternative Name: RAB35

Background: Synonyms:RAB1C, RAY Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate(PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth.

Molecular Weight: 25 kDa

Gene ID: 11021

UniProt: Q15286