RQCD1 antibody

Catalog No. ABIN7118331

The Rabbit Polyclonal anti-RQCD1 antibody (ABIN7118331) specifically detects RQCD1 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RQCD1 antibody (ABIN7118331)

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RQCD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RQCD1 Antibody

Purpose: CNOT9 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RCD1 required for cell differentiation1 homolog(S. pombe)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RQCD1

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Alternative Name: CNOT9

Background:

Synonyms: CCR4-NOT transcription complex subunit 9|Cell differentiation protein RQCD1 homolog (Rcd-1)|CNOT9|RCD1|RQCD1

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB-and JUN-dependent transcription. May play a role in cell differentiation(By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T(in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.

Molecular Weight: 30-40 kDa

Gene ID: 9125

UniProt: Q92600

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling