RAMP3 antibody

Catalog No. ABIN7118339

The Rabbit Polyclonal anti-RAMP3 antibody has been validated for WB, ELISA and IHC. It is suitable to detect RAMP3 in samples from Human and Mouse.

Quick Overview for RAMP3 antibody (ABIN7118339)

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RAMP3 Antibody

Purpose: RAMP3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: receptor(G protein-coupled) activity modifying protein 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RAMP3

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Alternative Name: RAMP3

Background:

Synonyms: Receptor activity-modifying protein 3|Calcitonin-receptor-like receptor activity-modifying protein 3 (CRLR activity-modifying protein 3)|RAMP3

Background: Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor(CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin(AM) together with CALCRL.

Molecular Weight: 50 kDa

Gene ID: 10268

UniProt: O60896

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling