ROR1 antibody (AA 30-200)

Catalog No. ABIN7118345

The Rabbit Polyclonal anti-ROR1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect ROR1 in samples from Human, Mouse and Rat.

Quick Overview for ROR1 antibody (AA 30-200) (ABIN7118345)

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ROR1 Antibody

Binding Specificity: AA 30-200

Purpose: ROR1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 30-200aa

Immunogen: receptor tyrosine kinase-like orphan receptor 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ROR1

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Alternative Name: ROR1

Background:

Synonyms: Inactive tyrosine-protein kinase transmembrane receptor ROR1|Neurotrophic tyrosine kinase, receptor-related 1|ROR1|NTRKR1

Background: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.

Molecular Weight: 130-140 kDa

Gene ID: 4919

UniProt: Q01973

Pathways: RTK Signaling, WNT Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha