RAPSN antibody

Catalog No. ABIN7118350

This Rabbit Polyclonal antibody specifically detects RAPSN in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RAPSN antibody (ABIN7118350)

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPSN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-RAPSN Antibody

Purpose: RAPSN antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: receptor-associated protein of the synapse

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RAPSN

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Alternative Name: RAPSN

Background:

Synonyms: 43 kDa receptor-associated protein of the synapse (RAPsyn)|43 kDa postsynaptic protein|Acetylcholine receptor-associated 43 kDa protein|RING finger protein 205|RAPSN|RNF205

Background: This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 43 kDa

Gene ID: 5913

UniProt: Q13702