Reticulon 3 antibody

Catalog No. ABIN7118415

The Rabbit Polyclonal anti-Reticulon 3 antibody (ABIN7118415) specifically detects Reticulon 3 in WB, ELISA, IHC and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Reticulon 3 antibody (ABIN7118415)

Target: Reticulon 3 (RTN3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Reticulon 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-Reticulon 3 Antibody

Purpose: RTN3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: reticulon 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Reticulon 3

Target: Reticulon 3 (RTN3)

Alternative Name: RTN3

Background:

Synonyms: Reticulon-3|Homolog of ASY protein (HAP)|Neuroendocrine-specific protein-like 2 (NSP-like protein 2)|Neuroendocrine-specific protein-like II (NSP-like protein II, NSPLII)|RTN3|ASYIP|NSPL2

Background: May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules(PubMed:25612671).

Molecular Weight: 24 kDa, 113 kDa

Gene ID: 10313

UniProt: O95197