RNASEL antibody

Catalog No. ABIN7118519

The Rabbit Polyclonal anti-RNASEL antibody is suitable to detect RNASEL in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for RNASEL antibody (ABIN7118519)

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RNASEL Antibody

Purpose: RNASEL antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RNASEL

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Alternative Name: RNASEL

Background:

Synonyms: 2-5A-dependent ribonuclease (2-5A-dependent RNase)|Ribonuclease 4|Ribonuclease L (RNase L)|RNASEL|RNS4

Background: This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

Molecular Weight: 110 kDa

Gene ID: 6041

UniProt: Q05823

Pathways: Hepatitis C