RBM15 antibody

Catalog No. ABIN7118672

The Rabbit Polyclonal anti-RBM15 antibody is suitable to detect RBM15 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for RBM15 antibody (ABIN7118672)

Target: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RBM15 Antibody

Purpose: RBM15 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RNA binding motif protein 15

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RBM15

Target: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Alternative Name: RBM15

Background:

Synonyms: RNA-binding protein 15|One-twenty two protein 1|RNA-binding motif protein 15|RBM15|OTT|OTT1

Background: May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.

Molecular Weight: 100-107 kDa

Gene ID: 64783

UniProt: Q96T37