RPGRIP1L antibody

Catalog No. ABIN7118723

The Rabbit Polyclonal anti-RPGRIP1L antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect RPGRIP1L in samples from Human.

Quick Overview for RPGRIP1L antibody (ABIN7118723)

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPGRIP1L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-RPGRIP1L Antibody

Purpose: RPGRIP1L antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RPGRIP1-like

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RPGRIP1L

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Alternative Name: RPGRIP1L

Background:

Synonyms: Protein fantom|Nephrocystin-8|RPGR-interacting protein 1-like protein (RPGRIP1-like protein)|RPGRIP1L|FTM|KIAA1005|NPHP8

Background: Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor(TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis(By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1 and NPHP4(By similarity). Does not seem to be strictly required for ciliogenesis(By similarity).

Molecular Weight: 151 kDa

Gene ID: 23322

UniProt: Q68CZ1

Pathways: DNA Replication, Regulation of G-Protein Coupled Receptor Protein Signaling, Synthesis of DNA