SEC14L1 antibody

Catalog No. ABIN7118816

The Rabbit Polyclonal anti-SEC14L1 antibody is suitable to detect SEC14L1 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for SEC14L1 antibody (ABIN7118816)

Target: SEC14L1 (SEC14-Like 1 (SEC14L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC14L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SEC14L1 Antibody

Purpose: SEC14L1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SEC14-like 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SEC14L1

Target: SEC14L1 (SEC14-Like 1 (SEC14L1))

Alternative Name: SEC14L1

Background:

Synonyms: SEC14-like protein 1|SEC14L1|SEC14L

Background: May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation(PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters(PubMed:17092608).

Molecular Weight: 81 kDa, 77 kDa

Gene ID: 6397

UniProt: Q92503