STK3 antibody

Catalog No. ABIN7118919

This anti-STK3 antibody is a Rabbit Polyclonal antibody detecting STK3 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for STK3 antibody (ABIN7118919)

Target: STK3 (serine/threonine Kinase 3 (STK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-STK3 Antibody

Purpose: STK3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: serine/threonine kinase 3 (STE20 homolog, yeast)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for STK3

Target: STK3 (serine/threonine Kinase 3 (STK3))

Alternative Name: STK3

Background:

Synonyms: Serine/threonine-protein kinase 3|Mammalian STE20-like protein kinase 2 (MST-2)|STE20-like kinase MST2|Serine/threonine-protein kinase Krs-1|Serine/threonine-protein kinase 3 36 kDa subunit (MST2/N)|Serine/threonine-protein kinase 3 20 kDa subunit (MST2/C)|STK3|KRS1|MST2

Background: This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 60 kDa

Gene ID: 6788

UniProt: Q13188

Pathways: Tube Formation