SRGAP1 antibody

Catalog No. ABIN7119133

This Rabbit Polyclonal antibody specifically detects SRGAP1 in ELISA, WB, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SRGAP1 antibody (ABIN7119133)

Target: SRGAP1 (SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGAP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-SRGAP1 Antibody

Purpose: SRGAP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SLIT-ROBO Rho GTPase activating protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SRGAP1

Target: SRGAP1 (SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1))

Alternative Name: SRGAP1

Background:

Synonyms: SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1)|Rho GTPase-activating protein 13|SRGAP1|ARHGAP13|KIAA1304

Background: GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

Molecular Weight: 130 kDa

Gene ID: 57522

UniProt: Q7Z6B7