SNRPB antibody

Catalog No. ABIN7119177

The Rabbit Polyclonal anti-SNRPB antibody (ABIN7119177) specifically detects SNRPB in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for SNRPB antibody (ABIN7119177)

Target: SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SNRPB Antibody

Purpose: SNRPB antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: A synthetic peptide(1-100AA)

Immunogen: small nuclear ribonucleoprotein polypeptides B and B1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SNRPB

Target: SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

Alternative Name: SNRPB

Background:

Synonyms: Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B)|Sm protein B/B' (Sm-B/B', SmB/B')|SNRPB|COD|SNRPB1

Background: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.

Molecular Weight: 25-30 kDa

Gene ID: 6628

UniProt: P14678

Pathways: Ribonucleoprotein Complex Subunit Organization