Sorbs2 antibody

Catalog No. ABIN7119344

The Rabbit Polyclonal anti-Sorbs2 antibody has been validated for ELISA and IP. It is suitable to detect Sorbs2 in samples from Human and Mouse.

Quick Overview for Sorbs2 antibody (ABIN7119344)

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorbs2 antibody is un-conjugated

Application: ELISA, Immunoprecipitation (IP)

Product Details anti-Sorbs2 Antibody

Purpose: SORBS2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: sorbin and SH3 domain containing 2

Isotype: IgG

Application Details

Application Notes: IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Alternative Name: SORBS2

Background:

Synonyms: Sorbin and SH3 domain-containing protein 2|Arg-binding protein 2 (ArgBP2)|Arg/Abl-interacting protein 2|Sorbin|SORBS2|ARGBP2|KIAA0777

Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12(PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Gene ID: 8470

UniProt: O94875