SNX9 antibody

Catalog No. ABIN7119367

This Rabbit Polyclonal antibody specifically detects SNX9 in WB, ELISA, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SNX9 antibody (ABIN7119367)

Target: SNX9 (Sorting Nexin 9 (SNX9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-SNX9 Antibody

Purpose: SNX9 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: sorting nexin 9

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SNX9

Target: SNX9 (Sorting Nexin 9 (SNX9))

Alternative Name: SNX9

Background:

Synonyms: Sorting nexin-9|SH3 and PX domain-containing protein 1 (Protein SDP1)|SH3 and PX domain-containing protein 3A|SNX9|SH3PX1|SH3PXD3A

Background: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.

Molecular Weight: 70-78 kDa

Gene ID: 51429

UniProt: Q9Y5X1