TRIP6 antibody

Catalog No. ABIN7119959

The Mouse Monoclonal anti-TRIP6 antibody is suitable to detect TRIP6 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and FACS.

Quick Overview for TRIP6 antibody (ABIN7119959)

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2G2

Product Details anti-TRIP6 Antibody

Purpose: TRIP6 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: thyroid hormone receptor interactor 6

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, FC:N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Alternative Name: TRIP6

Background:

Synonyms: Thyroid receptor-interacting protein 6 (TR-interacting protein 6, TRIP-6)|Opa-interacting protein 1 (OIP-1)|Zyxin-related protein 1 (ZRP-1)|TRIP6|OIP1

Background: Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.

Molecular Weight: 50 kDa

Gene ID: 7205

UniProt: Q15654

Pathways: Cell-Cell Junction Organization