TPRKB antibody

Catalog No. ABIN7120028

The Rabbit Polyclonal anti-TPRKB antibody has been validated for WB and ELISA. It is suitable to detect TPRKB in samples from Human, Rat and Mouse.

Quick Overview for TPRKB antibody (ABIN7120028)

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPRKB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TPRKB Antibody

Purpose: TPRKB antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: TP53RK binding protein

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TPRKB

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Alternative Name: TPRKB

Background:

Synonyms: EKC/KEOPS complex subunit TPRKB|PRPK-binding protein|TP53RK-binding protein|TPRKB

Background: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37(t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP(TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification(By similarity).

Molecular Weight: 20 kDa

Gene ID: 51002

UniProt: Q9Y3C4