TCF4 antibody

Catalog No. ABIN7120056

The Rabbit Polyclonal anti-TCF4 antibody (ABIN7120056) specifically detects TCF4 in WB, ELISA, IHC and IP. The antibody is reactive with Human and Mouse samples.

Quick Overview for TCF4 antibody (ABIN7120056)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-TCF4 Antibody

Purpose: TCF4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: transcription factor 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4

Background:

Synonyms: Transcription factor 4 (TCF-4)|Class B basic helix-loop-helix protein 19 (bHLHb19)|Immunoglobulin transcription factor 2 (ITF-2)|SL3-3 enhancer factor 2 (SEF-2)|TCF4|BHLHB19|ITF2|SEF2

Background: Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box(5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element(SSTR2-INR) to activate transcription(By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.

Molecular Weight: 72 kDa

Gene ID: 6925

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus