Transferrin Receptor antibody (AA 511-751)

Catalog No. ABIN7120097

The Mouse Monoclonal anti-Transferrin Receptor antibody has been validated for FACS, WB, IHC, ELISA, IF and IP. It is suitable to detect Transferrin Receptor in samples from Human.

Quick Overview for Transferrin Receptor antibody (AA 511-751) (ABIN7120097)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 4F3

Product Details anti-Transferrin Receptor Antibody

Binding Specificity: AA 511-751

Purpose: TFRC antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 511-751aa

Immunogen: transferrin receptor protein 1

Isotype: IgG2a

Application Details

Application Notes: WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: TFRC

Background:

Synonyms: Transferrin receptor protein 1 (TR, TfR, TfR1, Trfr)|T9|p90|Transferrin receptor protein 1, serum form (sTfR)|TFRC|CD71

Background: CD71, also known as transferrin receptor protein 1(TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.

Molecular Weight: 90 kDa

Gene ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis