TRIM6 antibody

Catalog No. ABIN7120296

The Rabbit Polyclonal anti-TRIM6 antibody (ABIN7120296) specifically detects TRIM6 in WB, ELISA and IHC. The antibody is reactive with Human and Rat samples.

Quick Overview for TRIM6 antibody (ABIN7120296)

Target: TRIM6 (Tripartite Motif Containing 6 (TRIM6))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TRIM6 Antibody

Purpose: TRIM6 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 229-422

Immunogen: tripartite motif-containing 6

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TRIM6

Target: TRIM6 (Tripartite Motif Containing 6 (TRIM6))

Alternative Name: TRIM6

Background:

Synonyms: Tripartite motif-containing protein 6|RING finger protein 89|RING-type E3 ubiquitin transferase TRIM6|TRIM6|RNF89

Background: E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).

Molecular Weight: 56 kDa

Gene ID: 117854

UniProt: Q9C030