TDRD5 antibody (AA 1-283)

Catalog No. ABIN7120381

This Rabbit Polyclonal antibody specifically detects TDRD5 in WB, ELISA, IHC and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for TDRD5 antibody (AA 1-283) (ABIN7120381)

Target: TDRD5 (Tudor Domain Containing 5 (TDRD5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDRD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-TDRD5 Antibody

Binding Specificity: AA 1-283

Purpose: TDRD5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-283aa

Immunogen: tudor domain containing 5

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TDRD5

Target: TDRD5 (Tudor Domain Containing 5 (TDRD5))

Alternative Name: TDRD5

Background:

Synonyms: Tudor domain-containing protein 5|TDRD5|TUDOR3

Background: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body(CB) assembly(By similarity).

Molecular Weight: 116 kDa

Gene ID: 163589

UniProt: Q8NAT2

Pathways: Ribonucleoprotein Complex Subunit Organization