TFIP11 antibody

Catalog No. ABIN7120384

This Mouse Monoclonal antibody specifically detects TFIP11 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for TFIP11 antibody (ABIN7120384)

Target: TFIP11 (Tuftelin Interacting Protein 11 (TFIP11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TFIP11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 3H5

Product Details anti-TFIP11 Antibody

Purpose: TFIP11 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tuftelin interacting protein 11

Isotype: IgG1

Application Details

Application Notes: WB: 1:200-1:1000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TFIP11

Target: TFIP11 (Tuftelin Interacting Protein 11 (TFIP11))

Alternative Name: TFIP11

Background:

Synonyms: Tuftelin-interacting protein 11|Septin and tuftelin-interacting protein 1 (STIP-1)|TFIP11|STIP

Background: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large(IL) and Intron Small(IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.

Molecular Weight: 97 kDa

Gene ID: 24144

UniProt: Q9UBB9