TWIST2 antibody

Catalog No. ABIN7120433

The Rabbit Polyclonal anti-TWIST2 antibody has been validated for WB and ELISA. It is suitable to detect TWIST2 in samples from Human and Mouse.

Quick Overview for TWIST2 antibody (ABIN7120433)

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWIST2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TWIST2 Antibody

Purpose: TWIST2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: twist homolog 2

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TWIST2

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Alternative Name: TWIST2

Background:

Synonyms: Twist-related protein 2|Class A basic helix-loop-helix protein 39 (bHLHa39)|Dermis-expressed protein 1 (Dermo-1)|TWIST2|BHLHA39|DERMO1

Background: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism(By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Molecular Weight: 21 kDa, 65 kDa

Gene ID: 117581

UniProt: Q8WVJ9

Pathways: Chromatin Binding