USP1 antibody

Catalog No. ABIN7120489

Product Details anti-USP1 Antibody

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200,IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for USP1

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Alternative Name: USP1 (USP1 Products)

Background: Synonyms:Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1 Background:Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).

Molecular Weight: 100 kDa

Gene ID: 7398

UniProt: O94782