USP48 antibody

Catalog No. ABIN7120525

This Rabbit Polyclonal antibody specifically detects USP48 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for USP48 antibody (ABIN7120525)

Target: USP48 (Ubiquitin Specific Peptidase 48 (USP48))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP48 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-USP48 Antibody

Purpose: USP48 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 48

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for USP48

Target: USP48 (Ubiquitin Specific Peptidase 48 (USP48))

Alternative Name: USP48

Background:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 48|Deubiquitinating enzyme 48|Ubiquitin thioesterase 48|Ubiquitin-specific peptidase 48|Ubiquitin-specific protease 48|Ubiquitin-specific-processing protease 48|USP48|USP31

Background: Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.

Molecular Weight: 119 kDa

Gene ID: 84196

UniProt: Q86UV5