USP49 antibody

Catalog No. ABIN7120526

The Rabbit Polyclonal anti-USP49 antibody is suitable to detect USP49 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IHC.

Quick Overview for USP49 antibody (ABIN7120526)

Target: USP49 (Ubiquitin Specific Peptidase 49 (USP49))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP49 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-USP49 Antibody

Purpose: USP49 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 49

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for USP49

Target: USP49 (Ubiquitin Specific Peptidase 49 (USP49))

Alternative Name: USP49

Background:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 49|Deubiquitinating enzyme 49|Ubiquitin thioesterase 49|Ubiquitin-specific-processing protease 49|USP49

Background: Specifically deubiquitinates histone H2B at 'Lys-120'(H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.

Molecular Weight: 73 kDa

Gene ID: 25862

UniProt: Q70CQ1