VAC14 antibody

Catalog No. ABIN7120699

This Rabbit Polyclonal antibody specifically detects VAC14 in ELISA, WB and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for VAC14 antibody (ABIN7120699)

Target: VAC14 (Vac14 Homolog (VAC14))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAC14 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-VAC14 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Vac14 homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:200-1:2000,IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for VAC14

Target: VAC14 (Vac14 Homolog (VAC14))

Alternative Name: VAC14

Background: Synonyms:ArPIKfyve, FLJ10305, FLJ36622, FLJ46582, Protein VAC14 homolog, Tax1 binding protein 2, TAX1BP2, TRX, VAC14, Vac14 homolog(S. cerevisiae) Background:The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate(PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate(PtdIns(3)P) and phosphatidylinositol 5-phosphate(PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles(ECV) / multivesicular bodies(MVB) transport intermediates from early endosomes.

Molecular Weight: 88 kDa,65 kDa

Gene ID: 55697

UniProt: Q08AM6

Pathways: Inositol Metabolic Process