VPS37A antibody

Catalog No. ABIN7120709

The Rabbit Polyclonal anti-VPS37A antibody has been validated for WB, IHC and ELISA. It is suitable to detect VPS37A in samples from Human, Mouse and Rat.

Quick Overview for VPS37A antibody (ABIN7120709)

Target: VPS37A (Vacuolar Protein Sorting 37 Homolog A (VPS37A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS37A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-VPS37A Antibody

Purpose: VPS37A antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: vacuolar protein sorting 37 homolog A

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for VPS37A

Target: VPS37A (Vacuolar Protein Sorting 37 Homolog A (VPS37A))

Alternative Name: VPS37A

Background:

Synonyms: Vacuolar protein sorting-associated protein 37A (hVps37A)|ESCRT-I complex subunit VPS37A|Hepatocellular carcinoma-related protein 1|VPS37A|HCRP1

Background: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 44 kDa

Gene ID: 137492

UniProt: Q8NEZ2