VAPA antibody

Catalog No. ABIN7120729

This Rabbit Polyclonal antibody specifically detects VAPA in WB, IHC, ELISA, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for VAPA antibody (ABIN7120729)

Target: VAPA (VAMP (Vesicle-Associated Membrane Protein)-Associated Protein A, 33kDa (VAPA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAPA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-VAPA Antibody

Purpose: VAPA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: VAMP(vesicle-associated membrane protein)-associated protein A, 33kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:50-1:200,IF: 1:10-1:100, IP: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for VAPA

Target: VAPA (VAMP (Vesicle-Associated Membrane Protein)-Associated Protein A, 33kDa (VAPA))

Alternative Name: VAPA

Background:

Synonyms: Vesicle-associated membrane protein-associated protein A (VAMP-A, VAMP-associated protein A, VAP-A)|33 kDa VAMP-associated protein (VAP-33)|VAPA|VAP33

Background: Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:25447204). With OSBPL3, may regulate ER morphology(PubMed:16143324). May play a role in vesicle trafficking(PubMed:11511104, PubMed:19289470).

Molecular Weight: 33 kDa

Gene ID: 9218

UniProt: Q9P0L0