VTA1 antibody

Catalog No. ABIN7120797

This anti-VTA1 antibody is a Rabbit Polyclonal antibody detecting VTA1 in ELISA, WB and IF. Suitable for Human, Mouse and Rat.

Quick Overview for VTA1 antibody (ABIN7120797)

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-VTA1 Antibody

Purpose: VTA1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Vps20-associated 1 homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000,IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: VTA1

Background:

Synonyms: Vacuolar protein sorting-associated protein VTA1 homolog|Dopamine-responsive gene 1 protein (DRG-1)|LYST-interacting protein 5 (LIP5)|SKD1-binding protein 1 (SBP1)|VTA1|C6orf55

Background: Involved in the endosomal multivesicular bodies(MVB) pathway. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR(By similarity). Involved in HIV-1 budding.

Molecular Weight: 45 kDa

Gene ID: 51534

UniProt: Q9NP79