WIPI1 antibody

Catalog No. ABIN7120833

This anti-WIPI1 antibody is a Rabbit Polyclonal antibody detecting WIPI1 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for WIPI1 antibody (ABIN7120833)

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-WIPI1 Antibody

Purpose: WIPI1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: WD repeat domain, phosphoinositide interacting 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for WIPI1

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Alternative Name: WIPI1

Background:

Synonyms: WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1)|Atg18 protein homolog|WD40 repeat protein interacting with phosphoinositides of 49 kDa (WIPI 49 kDa)|WIPI1|WIPI49

Background: This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.

Molecular Weight: 46 kDa

Gene ID: 55062

UniProt: Q5MNZ9

Pathways: Nuclear Hormone Receptor Binding, ER-Nucleus Signaling