ZBTB7B antibody

Catalog No. ABIN7120925

The Rabbit Polyclonal anti-ZBTB7B antibody has been validated for WB, ELISA, IF and IP. It is suitable to detect ZBTB7B in samples from Human, Mouse and Rat.

Quick Overview for ZBTB7B antibody (ABIN7120925)

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB7B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-ZBTB7B Antibody

Purpose: ZBTB7B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: zinc finger and BTB domain containing 7B

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IF: 1:10-1:100, IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ZBTB7B

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Alternative Name: ZBTB7B

Background:

Synonyms: Zinc finger and BTB domain-containing protein 7B|Krueppel-related zinc finger protein cKrox (hcKrox)|T-helper-inducing POZ/Krueppel-like factor|Zinc finger and BTB domain-containing protein 15|Zinc finger protein 67 homolog (Zfp-67)|Zinc finger protein 857B|Zinc finger protein Th-POK|ZBTB7B|ZBTB15|ZFP67|ZNF857B

Background: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors(thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes(By similarity).

Molecular Weight: 58 kDa

Gene ID: 51043

UniProt: O15156