ZW10 antibody

Catalog No. ABIN7121086

This Rabbit Polyclonal antibody specifically detects ZW10 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ZW10 antibody (ABIN7121086)

Target: ZW10 (Zw10 Kinetochore Protein (ZW10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZW10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ZW10 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ZW10, kinetochore associated, homolog(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ZW10

Target: ZW10 (Zw10 Kinetochore Protein (ZW10))

Alternative Name: ZW10

Background: Synonyms:HZW10, KNTC1AP, ZW10 Background:Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum(ER), the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241).

Molecular Weight: 90 kDa

Gene ID: 9183

UniProt: O43264