ZWILCH antibody

Catalog No. ABIN7121087

The Rabbit Polyclonal anti-ZWILCH antibody has been validated for WB, ELISA and IHC. It is suitable to detect ZWILCH in samples from Human, Mouse and Rat.

Quick Overview for ZWILCH antibody (ABIN7121087)

Target: ZWILCH (Zwilch, Kinetochore Associated, Homolog (ZWILCH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZWILCH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ZWILCH Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Zwilch, kinetochore associated, homolog(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ZWILCH

Target: ZWILCH (Zwilch, Kinetochore Associated, Homolog (ZWILCH))

Alternative Name: ZWILCH

Background: Synonyms:FLJ10036, FLJ16343, hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH Background:Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:15824131).

Molecular Weight: 67 kDa

Gene ID: 55055

UniProt: Q9H900