PFKFB1 antibody (AA 21-120) (HRP)

Catalog No. ABIN708245

The Rabbit Polyclonal anti-PFKFB1 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect PFKFB1 in samples from Mouse.

Quick Overview for PFKFB1 antibody (AA 21-120) (HRP) (ABIN708245)

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKFB1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PFKFB1 Antibody (HRP)

Binding Specificity: AA 21-120

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PFKFB1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PFKFB1

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Alternative Name: PFKFB1

Background:

Synonyms: 6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 1, 6-bisphosphatase, 6-P2ase 1, 6-P2ASE liver isozyme, 6PF 2 K/Fru 2 6 P2ASE liver isozyme, 6PF 2 K/Fru 2,6 P2ase 1, 6PF-2-K/Fru-2, F261_HUMAN, F6PK, Fructose 2 6 bisphosphatase, Fructose 6 phosphate 2 kinase:fructose 2 6 bisphosphatase, Fructose-2, HL2K, MGC116715, MGC116717, PFK/FBPase 1, PFKFB 1, Pfkfb1, PFRX.

Background: PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.

Gene ID: 5207

Pathways: Regulation of Carbohydrate Metabolic Process