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Follistatin antibody

This anti-Follistatin antibody is a Mouse Monoclonal antibody detecting Follistatin in ELISA and IHC (f). Suitable for Human.
Catalog No. ABIN7126189

Quick Overview for Follistatin antibody (ABIN7126189)

Target

See all Follistatin (FST) Antibodies
Follistatin (FST)

Reactivity

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Human

Host

  • 43
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Mouse

Clonality

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Monoclonal

Conjugate

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  • 1
This Follistatin antibody is un-conjugated

Application

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ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Specificity

    Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS288 is the main cell-surface form and binds to surface heparin sulphate proteoglycans. FST/4281 is a clone raised against recombinant Fst 288, and is used in combination, commonly as the capture, with antibody FST/4282 in a two site ELISA for the detection of Follistatin.

    Cross-Reactivity (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Raised to human Follistatin (Fst) 288 and recognizes both human Fst 288 and 315

    Isotype

    IgG1
  • Application Notes

    Known_Application: ELISA (Use in combination with clone FST/4282 for two-site ELISA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human testis or ovary.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Preservative

    Azide free

    Storage

    -20 °C,-80 °C

    Storage Comment

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Expiry Date

    24 months
  • Target

    Follistatin (FST)

    Alternative Name

    FST

    Background

    Follistatin, FS, FST, Active-binding protein,Follistatin / Activin Binding Protein
    Cellular localisation: Secreted.

    Molecular Weight

    37kDa

    Gene ID

    10468, 9914

    UniProt

    P19883

    Pathways

    Negative Regulation of Hormone Secretion
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