TCF25 antibody

Catalog No. ABIN7126395

Product Details anti-TCF25 Antibody

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCF25 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

Cross-Reactivity (Details): Human. Predicted to react with Mouse and Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human TCF25 protein

Isotype: IgG1

Application Details

Application Notes:

Known_Application: Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for TCF25

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Alternative Name: TCF25 (TCF25 Products)

Background: FKSG26, hKIAA1049, Hulp1, KIAA1049, Nuclear localized protein 1, NULP1, PRO2620, Transcription factor 25 (basic helix loop helix),TCF25
Cellular localisation: Nucleus. Some staining in the cytosol.

Molecular Weight: 77kDa

Gene ID: 22980, 415342

UniProt: Q9BQ70