HIC2 antibody
Quick Overview for HIC2 antibody (ABIN7126402)
Target
See all HIC2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- HIC2 (HIC ZBTB Transcriptional Repressor 2) is a Protein Coding gene. Diseases associated with HIC2 include Orofaciodigital Syndrome X and Simpson-Golabi-Behmel Syndrome, Type 1. HIC2 contains 5 C2H2-type zinc fingers and 1 BTB (POZ) domain. It belongs to the krueppel C2H2-type zinc-finger protein family, Hic subfamily and is a transcriptional repressor. It is a transcription activator of SIRT1.
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Cross-Reactivity (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human HIC2protein
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Isotype
- IgG2b
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Application Notes
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- HIC2 (Hypermethylated in Cancer 2 (HIC2))
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Alternative Name
- HIC2
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Background
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HRG22, KIAA1020, ZBTB30, ZNF907,HIC2 (Hypermethylated in cancer 2) (Transcriptional Repressor)
Cellular localisation: Nucleus. -
Molecular Weight
- 66.1kDa
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Gene ID
- 23119, 632767
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UniProt
- Q96JB3
Target
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