FOSL2 antibody

Catalog No. ABIN7126433

This Mouse Monoclonal antibody specifically detects FOSL2 in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for FOSL2 antibody (ABIN7126433)

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOSL2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-FOSL2 Antibody

Specificity: The Fos related gene, Fra-2, was initially molecularly cloned from chicken genomic DNA and shown to represent a new member of the immediate early gene family. The human counterpart of the chicken Fra-2 gene has since been described. Sequence alignment shows that the amino acid sequences conserved among Fra-2, c-Fos, Fra-1 and Fos B are contained in five regions. Region 2, the longest and most highly conserved region, contains the leucine zipper structure and the basic region, suggesting that like Fos, Fra-1 and Fos B, Fra-2 also forms heterodimers with c-Jun that recognize a specific DNA sequence such as the binding site for transcription factor AP-1. Such a model is further supported by the finding that the Fra-2 gene product forms a complex with c-Jun in growth-stimulated cells

Cross-Reactivity (Details): Human

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human FOSL2 protein

Isotype: IgG1

Application Details

Application Notes:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, MCF7 or 293T cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for FOSL2

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Alternative Name: FOSL2

Background: FLJ23306, FOS like antigen 2, Fos-related antigen 2 (FRA-2), Fosl2,Fos-related antigen 2 (FRA-2) / FOS-like antigen 2 (FOSL2)
Cellular localisation: Nucleus.

Molecular Weight: 40kDa

Gene ID: 2355

UniProt: P15408

Pathways: Feeding Behaviour, Photoperiodism