CD235a/GYPA antibody

Catalog No. ABIN7126498

This anti-CD235a/GYPA antibody is a Mouse Monoclonal antibody detecting CD235a/GYPA in FACS and IF. Suitable for Human.

Quick Overview for CD235a/GYPA antibody (ABIN7126498)

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD235a/GYPA antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-CD235a/GYPA Antibody

Specificity: Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Cross-Reactivity (Details): Human. Others-not tested.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Human erythrocytes treated with neuraminidase

Isotype: IgG2a

Application Details

Application Notes:

Known_Application: Flow Cytometry (0.5-1 μg/million cells), ,Immunofluorescence (0.5-1 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: Erythrocytes

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for CD235a/GYPA

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Alternative Name: GYPA

Background: Blood group--MN locus, GPA, GPErik, GpMiIII, GPSAT, GYPA, MN sialoglycoprotein, MNS, PAS2, Sialoglycoprotein alpha,Glycophorin A / CD235a (Erythrocyte Marker)
Cellular localisation: Cell Surface

Molecular Weight: 39kDa

Gene ID: 2993, 2994

UniProt: P02724

Pathways: Maintenance of Protein Location