ZNF81 antibody
Quick Overview for ZNF81 antibody (ABIN7126545)
Target
See all ZNF81 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNAbinding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF81, also known as HFZ20 or MRX45, is a transcriptional regulator belonging to the krueppel C2H2-type zincfinger protein family. It localizes to the nucleus and contains 12 C2H2-type zinc fingers and one KRAB domain. Mutations in the gene encoding ZNF81 are implicated in nonsyndromic X-linked mental retardation (XLMR).
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Cross-Reactivity (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human ZNF81 protein
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Isotype
- IgG2b
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Application Notes
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Known_Application: ELISA (For coating, order antibody without BSA), ,Western Blot (1-2 μg/mL),Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- ZNF81 (Zinc Finger Protein 81 (ZNF81))
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Alternative Name
- ZNF81
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Background
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HFZ20, Mental Retardation, X-linked 45 (MRX45),ZNF81 / Zinc finger protein 81 (Transcription Factor)
Cellular localisation: Nucleus. Cytoplasm (granular). -
Molecular Weight
- 75.9kDa
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Gene ID
- 347344, 504609
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UniProt
- P51508
Target
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