Recombinant ODC1 antibody
Quick Overview for Recombinant ODC1 antibody (ABIN7126752)
Target
See all ODC1 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
-
-
Specificity
- Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
-
Cross-Reactivity (Details)
- Human, Mouse, Rat.
-
Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
Immunogen
- Recombinant full-length human ODC-1 protein
-
Isotype
- IgG1
-
-
-
-
Application Notes
-
Known_Application: ELISA (For coating, order antibody without BSA), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: PC3 cells.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
Preservative
- Azide free
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
Expiry Date
- 24 months
-
-
- ODC1 (Ornithine Decarboxylase 1 (ODC1))
-
Alternative Name
- ODC1
-
Background
-
Ornithine decarboxylase structural 1, RNODC,Ornithine Decarboxylase-1 (ODC-1)
Cellular localisation: Cytoplasmic -
Molecular Weight
- 53kDa
-
Gene ID
- 4953, 467701
-
UniProt
- P11926
Target
-