ITLN1/Omentin antibody (AA 16-141)

Catalog No. ABIN7126828

This anti-ITLN1/Omentin antibody is a Mouse Monoclonal antibody detecting ITLN1/Omentin in IHC (f). Suitable for Human.

Quick Overview for ITLN1/Omentin antibody (AA 16-141) (ABIN7126828)

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITLN1/Omentin antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Product Details anti-ITLN1/Omentin Antibody

Binding Specificity: AA 16-141

Specificity: Human intelectin-1 (ITLN-1) is a novel identified galactose binding lectin that is usually expressed in the heart, small intestine, and colon. In normal tissues, human intelectin-1 was mainly secreted from gastrointestinal goblet cells along with mucus into the intestinal lumen, and it was also expressed, to a lesser extent, in mesothelial cells and urinary epithelial cells. It is overexpressed in human malignant pleural mesothelioma (MPM). In contrast, sarcomatoid-type MPMs, biphasic MPMs, and poorly differentiated MPMs are rarely positive for intelectin-1, and it is not expressed in other cancers, except in mucus-producing adenocarcinoma.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa16-141) of human Intelectin-1 (ITLN1) protein (exact sequence is proprietary)

Isotype: IgG2

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human mesothelioma or colon tissue.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ITLN1/Omentin

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Alternative Name: ITLN1

Background: Endothelial lectin HL-1, Galactofuranose binding lectin, hIntL, Intestinal lactoferrin receptor, INTL, ITLN, LFR,Intelectin 1 / Omentin (Epithelioid-Type Malignant Mesothelioma Marker)
Cellular localisation: Cell membrane. Secreted.

Molecular Weight: 35kDa

Gene ID: 55600, 50813

UniProt: Q8WWA0