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Recombinant CD2 antibody (N-Term)

The Rabbit Monoclonal anti-CD2 antibody has been validated for WB and IHC (f). It is suitable to detect CD2 in samples from Human.
Catalog No. ABIN7127128

Quick Overview for Recombinant CD2 antibody (N-Term) (ABIN7127128)

Target

See all CD2 Antibodies
CD2

Antibody Type

Recombinant Antibody

Reactivity

  • 178
  • 42
  • 32
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Human

Host

  • 143
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Rabbit

Clonality

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  • 59
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Monoclonal

Conjugate

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This CD2 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Binding Specificity

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    N-Term

    Specificity

    CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.

    Cross-Reactivity (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant fragment corresponding to N-terminal of human CD2 protein

    Isotype

    IgG
  • Application Notes

    Known_Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human tonsil, spleen or lymph node.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Preservative

    Azide free

    Storage

    -20 °C,-80 °C

    Storage Comment

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Expiry Date

    24 months
  • Target

    CD2

    Alternative Name

    CD2

    Background

    Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11,CD2 / Lymphocyte Function Antigen 2 (LFA-2)
    Cellular localisation: Cell surface

    Molecular Weight

    39kDa

    Gene ID

    914, 523500

    UniProt

    P06729
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