ADIPOQ antibody

Catalog No. ABIN7127172

This Mouse Monoclonal antibody specifically detects ADIPOQ in WB, ELISA and Coat. It exhibits reactivity toward Human.

Quick Overview for ADIPOQ antibody (ABIN7127172)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADIPOQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Coating (Coat)

Product Details anti-ADIPOQ Antibody

Specificity: This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. (Hotta K, et al.) Clone ADPN/4255 is also used in a combination ELISA with clone ADPN/4256, acting as the detection antibody.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Synthetic peptide corresponding to the globular head region of the Adiponectin molecule.

Isotype: IgG1

Application Details

Application Notes:

Known_Application: ELISA (For coating, use antibody without BSA), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Human kidney.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Alternative Name: ADIPOQ

Background: Adiponectin, Adipocyte complement-related 30 kDa protein (ACRP30), Adipocyte-specific secretory protein, Adiponectin, C1Q and collagen domain containing (ACDC), ADIPOQ, Adipose most abundant gene transcript 1 protein, Adipose specific collagen like factor, ADIPQTL1, ADPN, APM-1, Gelatin-binding protein 28 (GBP28),Adiponectin (Marker of Obesity)
Cellular localisation: Cytoplasm and cell surface.

Molecular Weight: 26-30kDa

Gene ID: 9370, 80485

UniProt: Q15848