Recombinant CD74 antibody
Quick Overview for Recombinant CD74 antibody (ABIN7127283)
Target
See all CD74 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Human
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:50-1:500,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD74 (HLA-DR-gamma (CD74))
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Alternative Name
- CD74
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Background
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Background: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Aliases: HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, Ii, p33, CD74, CD74, DHLAG
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UniProt
- P04233
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Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
Target
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