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Recombinant CD74 antibody

The Rabbit Monoclonal anti-CD74 antibody has been validated for FACS, IHC and ELISA. It is suitable to detect CD74 in samples from Human.
Catalog No. ABIN7127283

Quick Overview for Recombinant CD74 antibody (ABIN7127283)

Target

See all CD74 Antibodies
CD74 (HLA-DR-gamma (CD74))

Antibody Type

Recombinant Antibody

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This CD74 antibody is un-conjugated

Application

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Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

Clone

8H11
  • Cross-Reactivity

    Human

    Purification

    Affinity-chromatography

    Immunogen

    A synthesized peptide

    Isotype

    IgG
  • Application Notes

    Recommended dilution: IHC:1:50-1:500,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    CD74 (HLA-DR-gamma (CD74))

    Alternative Name

    CD74

    Background

    Background: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

    Aliases: HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, Ii, p33, CD74, CD74, DHLAG

    UniProt

    P04233

    Pathways

    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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