Recombinant BACE1 antibody

Catalog No. ABIN7127360

This Rabbit Monoclonal antibody specifically detects BACE1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Recombinant BACE1 antibody (ABIN7127360)

Target: BACE1 (Beta-secretase 1 (BACE1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 7G3

Product Details anti-BACE1 Antibody

Purpose: BACE1 Recombinant Monoclonal Antibody

Cross-Reactivity: Mouse, Rat

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human BACE1

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1

Background:

Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Aliases: Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2), BACE1, BACE KIAA1149

UniProt: P56817