Recombinant OPRD1 antibody
Quick Overview for Recombinant OPRD1 antibody (ABIN7127652)
Target
See all OPRD1 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Human, Mouse
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human OPRD1
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:500-1:5000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- OPRD1 (Opioid Receptor, delta 1 (OPRD1))
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Alternative Name
- OPRD1
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Background
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Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Aliases: Delta-type opioid receptor (D-OR-1) (DOR-1), OPRD1, OPRD
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UniProt
- P41143
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Pathways
- Protein targeting to Nucleus
Target
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