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Recombinant HSP27 antibody (pSer78)

The Rabbit Monoclonal anti-HSP27 antibody has been validated for WB, IHC and ELISA. It is suitable to detect HSP27 in samples from Human.
Catalog No. ABIN7127700

Quick Overview for Recombinant HSP27 antibody (pSer78) (ABIN7127700)

Target

See all HSP27 (HSPB1) Antibodies
HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Antibody Type

Recombinant Antibody

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This HSP27 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone

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    pSer78

    Cross-Reactivity

    Human

    Purification

    Affinity-chromatography

    Immunogen

    A synthesized peptide derived from human Phospho-HSPB1 (S78)

    Isotype

    IgG
  • Application Notes

    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

    Alternative Name

    HSPB1

    Background

    Background: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).

    Aliases: Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27, SRP27, HSPB1, HSP27, HSP28

    UniProt

    P04792

    Pathways

    MAPK Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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